Overview
This diagram shows the 'life-cycle' of a depressive illness - starting with predisposing factors, then the immediate triggering factors, moving on to the treatment phase and then the outcomes – and shows how our research streams target key points within that life-cycle. To see a short description of each of the Research Streams hold your cursor over that stream – you can also link to current studies in each Research Stream.

Stream 1 – Determinants and Phenomenology
Studies in this stream reflect our long-standing interest in integrating both the psychosocial and biological causes of mood disorders.

Stream 2 – Vulnerability, Resilience and Quest
These studies look at the importance of resilience as a protective factor against the depressive disorders.

Stream 3 – Assessment and Innovative Interventions
These studies:

• Advance assessment techniques
• Improve understanding of why a particular treatment is effective in a particular disorder or depressive type,
• Help to identify treatments that are better targeted for each individual
• Assist in developing new interventions where no effective treatments exist.

Stream 4 – Studying Treatment Resistance
In this stream our studies focus on devising a clinically meaningful model of treatment resistance that helps in understanding the causes and makes therapy more rational.

Stream 5 – Functioning, Disability and Other Sequelae
Studies in this stream assess the long-term disability and burden of depressive and bipolar disorders and their causes.